Insulin-sensitive Tissues Assignment

Insulin-sensitive Tissues Assignment

Insulin-sensitive Tissues Assignment

Insulin-sensitive Tissues Assignment

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Question 11. Question : The goals of therapy when prescribing HRT include reducing: Cardiovascular risk Risk of stroke or other thromboembolic event Breast cancer risk Vasomotor symptoms Question 12. Question : Patients who have angina, regardless of class, who are also diabetic should be on: Nitrates Beta blockers ACE inhibitors Calcium channel blockers Question 13. Question : The New York Heart Association and the Canadian Cardiovascular Society have described grading criteria for levels of angina. Angina that occurs with unusually strenuous activity or on walking or climbing stair after meals is: Class I Class II Class III Class IV Question 14. Question : Patients with allergic rhinitis may benefit from a prescription of: Fluticasone (Flonase) Cetirizine (Zyrtec) OTC cromolyn nasal spray (Nasalcrom) Any of the above Question 15. Question : Kyle has Crohn’s disease and has a documented folate deficiency. Drug therapy for folate deficiency anemia is: Oral folic acid 1 to 2 mg/day Oral folic acid 1 gm/day IM folate weekly for at least six months Oral folic acid 400 mcg daily Question 16. Question : The treatment for vitamin B12 deficiency is: 1,000 mcg daily of oral cobalamin 2 gm/day of oral cobalamin 100 mcg/day vitamin B12 IM 500 mcg/dose nasal cyanocobalamin two sprays once a week Question 17. Question : Nonadherence is especially common in drugs that treat asymptomatic conditions, such as hypertension. One way to reduce the likelihood of nonadherence to these drugs is to prescribe a drug that: Has a short half-life so that missing one dose has limited effect Requires several dosage titrations so that missed doses can be replaced with lower doses to keep costs down Has a tolerability profile with less of the adverse effects that are considered “irritating,” such as nausea and dizziness Must be taken no more than twice a day Question 18. Question : Type II diabetes is a complex disorder involving: Absence of insulin production by the beta cells A suboptimal response of insulin-sensitive tissues in the liver Increased levels of GLP in the postprandial period Too much fat uptake in the intestine Question 19. Question : Metformin is a primary choice of drug to treat hyperglycemia in type II diabetes because it: Substitutes for insulin usually secreted by the pancreas Decreases glycogenolysis by the liver Increases the release of insulin from beta cells Decreases peripheral glucose utilization Question 20. Question : Gender differences between men and women in pharmacokinetics include: More rapid gastric emptying so that drugs absorbed in the stomach have less exposure to absorption sites Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of distribution Increased levels of bile acids so that drugs metabolized in the intestine have higher concentrations Slower organ blood flow rates so that drugs tend to take longer to be excreted Question 21. Question : If not chosen as the first drug in hypertension treatment, which drug class should be added as the second step because it will enhance the effects of most other agents? ACE inhibitors Beta blockers Calcium channel blockers Diuretics

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